Wellbutrin (Bupropion hydrochloride) for Autism

Overview

Wellbutrin is a prescription drug approved by the Food and Drug Administration (FDA) in 1985 to treat depression. In children with autism spectrum disorders (ASD), Wellbutrin may be effective in treating depression and attention deficit hyperactivity disorder (ADHD). Wellbutrin is also known by its drug name, Bupropion hydrochloride.

Wellbutrin is not appropriate for people with a history of seizures, anorexia, and sensitivity to Bupropion or similar drugs. Wellbutrin be used with caution in people with depression, high blood pressure, bipolar disorder, and psychosis.

Wellbutrin is an antidepressant. Wellbutrin is believed to work by changing the balance of neurotransmitters in the brain.

How do I take it?
Your doctor will likely begin your child on a low dose of Wellbutrin and increase the dosage gradually in order to avoid side effects.

Wellbutrin is taken orally two or three times a day. Wellbutrin may be taken with or without food.

Always follow your doctor’s instructions exactly when taking Wellbutrin.

Results
Clinical research on Bupropion (Wellbutrin) in children with ASD is limited. However, research indicates that Wellbutrin may be effective in treating depression and ADHD in autistic children.

Side effects
Serious side effects of Wellbutrin in children, adolescents, and young adults can include suicidal thoughts and worsening of depression. Wellbutrin can also cause seizures, psychosis, mania, and high blood pressure.

Common side effects of Wellbutrin can include dry mouth, strange taste in the mouth, nausea, headache, vomiting, constipation, sweating, aching joints, blurry vision, anxiety, irritability, insomnia, or dizziness.

Notify your doctor if you experience suicidal thoughts while taking Wellbutrin.

Many drugs can cause allergic reactions that, in the most serious cases, can result in death. Seek immediate medical help if you experience signs of a severe allergic reaction such as difficulty breathing or swelling in the face, throat, eyes, lips or tongue.